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GLUCOSE TOLERANCE TEST

The glucose tolerance test is a medical test in which glucose is given and blood sample take forward to determination how quick it is cleared from the blood.

BIOCHEMISTRY

Himanshu Paneru

4/4/20242 मिनट पढ़ें

GLUCOSE TOLERANCE TEST

· The glucose tolerance test is a medical test in which glucose is given and blood sample take forward to determination how quick it is cleared from the blood.

· GTT plays a crucial role in diagnosing disorders related to glucose metabolism, such as diabetes mellitus and pre-diabetes.

· There are several types of GT used in different condition but the most common one of them is oral glucose test or OGTT.

· Glucose serves as the primary source of energy for cells in the human body.

· The GTT is usually given to pregnant women’s during 24th and 28th week of pregnancy.

· This test is also given to pregnant who has diabetic symptoms.

· Beside that GTT is also given to the patient who have high Glucose level in blood.

PREPRATION OF GTT

· Inform the doctor about the varied prescription of drug you are taking because certain drug can be false result

· Have a normal diet like any other day

· Fasting is required for 8 to 10 hours you might want to avoid using the washroom period to testing as urine samples may be needed

· on margin of testing do not smoke or have coffee or caffeine based product

· GTT is not done in sick person

GTT PROCEDURE

· Collect a baseline blood sample from the patient, usually by venipuncture, to measure fasting blood glucose levels.

· Prepare a glucose solution containing a standardized amount of glucose dissolved in water.

· Now tell the patient to drink the solution in 5 - 10 minute duration.

· After the ingestion of the glucose solution.

· Collect the blood sample at interval of 30 minutes, 1 hours or sometime 2 hours.

· After the test sample is measured in laboratory through enzymatic assays or automated analyzers.

RESULT

· Fasting Blood Glucose: 95 mg/dL

· 1-Hour Post-Glucose: 165 mg/dL

· 2-Hour Post-Glucose: 130 mg/dL

· 3-Hour Post-Glucose: 110 mg/dL

· Fasting Blood Glucose: The fasting blood glucose level of 95 mg/dL falls within the normal range (typically less than 100 mg/dL), indicating no fasting hyperglycemia.

· Post-Glucose Levels:

1-Hour Post-Glucose: The blood glucose level at 1 hour post-glucose ingestion is 165 mg/dL. This value exceeds the normal range (typically less than 140 mg/dL), suggesting impaired glucose tolerance.

2-Hour Post-Glucose: The blood glucose level at 2 hours post-glucose ingestion is 130 mg/dL, which is within the normal range. However, it's important to note that the value was elevated at the 1-hour mark.

3-Hour Post-Glucose: The blood glucose level at 3 hours post-glucose ingestion is 110 mg/dL, remaining within the normal range.

GTT NORMAL VALUE

· Fasting Blood Glucose: 95 mg/dL

· 1-Hour Post-Glucose: 165 mg/dL

· 2-Hour Post-Glucose: 130 mg/dL

· 3-Hour Post-Glucose: 110 mg/dL

BLOOD GLUCOSE LEVEL

· The normal blood glucose level is 70-110 mg/dl

· Post meal plasma glucose 110-140 mg/dl

· Random plasma glucose 72-110 mg/dl

SIDE EFFECTS OF GTT

· There is a risk attached with GTT which are follows